RPGeNet version 2 has been released.
We encourage using the new version, enjoy it!
This framework represents the retinitis pigmentosa gene interaction network, built upon
110 RP/LCA driver genes. It combines data from the iHOP, BioGRID, and STRING repositories,
with additional information from GeneOntology, GeneCards, OMIM, UniProt, RefSeq, and UCSC.
Further details are available on the RPGeNet paper:
"Distilling a Visual Network of Retinitis Pigmentosa Gene-Protein Interactions
to Uncover New Disease Candidates"
Boloc et al, PLoS ONE, 2015, 10(8): e0135307
How to use RPGeNet
Input query genes separated by commas, semicolons and/or spaces (case insensitive) in order
to visualize a focused network on the query then click on "Explore Network", or choose one of the 110 RP/LCA driver genes from the dropdown list to visualize the paths that this gene
shares with other RP/LCA genes and click "Get Path Genes". Here you have some examples of query genes:
| ||Single Genes: ||CERKL |
| ||Multiple Genes: ||EYS, RHO, cerkl,RP1 |